Effect of 12 Weeks of Endurance Training Combined with Creatine Supplement, Photobiomodulation Therapy, or Both on Performance and Muscle Damage in Rats

dc.contributor.authorMalta, Elvis de Souza [UNESP]
dc.contributor.authorFerraresi, Cleber
dc.contributor.authorMonte, Marina Gaiato [UNESP]
dc.contributor.authorPoli, Rodrigo Araujo Bonetti de [UNESP]
dc.contributor.authorBjordal, Jan Magnus
dc.contributor.authorLopes-Martins, Rodrigo Alvaro Brandao
dc.contributor.authorMarcos, Rodrigo Labat
dc.contributor.authorZagatto, Alessandro Moura [UNESP]
dc.contributor.authorCarvalho, Rodrigo Leal de Paiva [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniv Brasil
dc.contributor.institutionUniv Bergen
dc.contributor.institutionUniv Vale Paraiba UNIVAP
dc.contributor.institutionUNINOVE Appl Biophoton Hlth Sci
dc.date.accessioned2020-12-10T20:04:15Z
dc.date.available2020-12-10T20:04:15Z
dc.date.issued2020-06-26
dc.description.abstractBackground:Photobiomodulation therapy (PBMT) and creatine (Cr) intake have been used in conjunction with heavy training, but little is known about their possible effects during a long-term training program. Objective:We assessed long-term use of PBMT and Cr in an exercise training program. Methods:Twenty-five male Wistar rats weighing similar to 300 g were randomly allocated to one of five groups: a nontraining control group, a training group, a training group receiving Cr, a training group receiving PBMT, and a training group receiving both PBMT and Cr. The training program consisted of 12 weeks of daily swimming training. PBMT was delivered in six points with a laser device (808 nm, 100 mW, 30 s per point of irradiation, 3 J, 75 J/cm(2)). Results:All training groups showed significantly higher peak force and longer time to 50% decay of force, and lower creatine kinase (CK) levels than the nontraining control group, thus confirming the benefit of the training program. In all outcomes related to muscle performance, the groups receiving PBMT with or without Cr supplement performed significantly better (p < 0.05) peak force and time of force decay during an electrical stimulation protocol than all the other groups. In addition, CK levels were also significantly lower for the PBMT groups than for the other groups. Conclusions:We conclude that PBMT alone or in conjunction with Cr supplement during a 12-week training program resulted in significantly better muscle performance and lower levels of CK, a biochemical marker of muscle damage.en
dc.description.affiliationSao Paulo State Univ UNESP, Postgrad Program Movement Sci, Lab Physiol & Sport Performance LAFIDE, Dept Phys Educ, Ave Eng Luiz Edmundo Carrijo Coube, BR-17033360 Bauru, SP, Brazil
dc.description.affiliationUniv Brasil, Postgrad Program Biomed Engn, Sao Paulo, SP, Brazil
dc.description.affiliationUNESP, Med Sch, Postgrad Program Pathophysiol, Med Clin, Botucatu, SP, Brazil
dc.description.affiliationUniv Bergen, Dept Global Publ Hlth & Primary Care, Physiotherapy Res Grp, Bergen, Norway
dc.description.affiliationUniv Vale Paraiba UNIVAP, Lab Biophoton & Expt Therapeut, Inst Res & Dev, Sao Jose Dos Campos, SP, Brazil
dc.description.affiliationUNINOVE Appl Biophoton Hlth Sci, Sao Paulo, SP, Brazil
dc.description.affiliationUnespSao Paulo State Univ UNESP, Postgrad Program Movement Sci, Lab Physiol & Sport Performance LAFIDE, Dept Phys Educ, Ave Eng Luiz Edmundo Carrijo Coube, BR-17033360 Bauru, SP, Brazil
dc.description.affiliationUnespUNESP, Med Sch, Postgrad Program Pathophysiol, Med Clin, Botucatu, SP, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: 2017/21724-8
dc.description.sponsorshipIdFAPESP: 2019/17445-1
dc.format.extent5
dc.identifierhttp://dx.doi.org/10.1089/photob.2019.4793
dc.identifier.citationPhotobiomodulation Photomedicine And Laser Surgery. New Rochelle: Mary Ann Liebert, Inc, 5 p., 2020.
dc.identifier.doi10.1089/photob.2019.4793
dc.identifier.urihttp://hdl.handle.net/11449/197039
dc.identifier.wosWOS:000546051200001
dc.language.isoeng
dc.publisherMary Ann Liebert, Inc
dc.relation.ispartofPhotobiomodulation Photomedicine And Laser Surgery
dc.sourceWeb of Science
dc.subjectlaser irradiation
dc.subjectendurance training
dc.subjectergogenic aids
dc.subjectmuscle performance
dc.subjectmuscle damage
dc.titleEffect of 12 Weeks of Endurance Training Combined with Creatine Supplement, Photobiomodulation Therapy, or Both on Performance and Muscle Damage in Ratsen
dc.typeArtigo
dcterms.rightsHolderMary Ann Liebert, Inc
unesp.author.orcid0000-0002-1361-8390[2]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt
unesp.departmentEducação Física - FCpt
unesp.departmentFisiologia - IBBpt

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