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The role of oxidative stress in renal injury related to obesity

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dc.contributor.authorPierine, Damiana Tortolero [UNESP]
dc.contributor.authorBiondo, Guilherme Augusto [UNESP]
dc.contributor.authorSilva, Vanessa dos Santos [UNESP]
dc.contributor.authorCorrêa, Camila Renata [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2016-04-01T18:43:37Z
dc.date.available2016-04-01T18:43:37Z
dc.date.issued2015
dc.description.abstractThe mechanisms linking obesity to kidney damage are unknown. AGEs are responsible for renal damage in obese individuals. The receptor AGEs (RAGE) contributes to nuclear transcription factors that result in the production of proinflammatory cytokines and this seems to contribute to the development of renal disease. Thus, intervention with antioxidant can have an important effect in the prevention and treatment of pro-oxidant and pro-inflammatory state in the kidneys resulting from obesity.en
dc.description.affiliationUnespUniversidade Estadual Paulista, Departamento de Patologia, Faculdade de Medicina de Botucatu
dc.description.affiliationUnespUniversidade Estadual Paulista, Departamento de Microbiologia e Imunologia, Instituto de Biociências de Botucatu
dc.description.affiliationUnespUniversidade Estadual Paulista, Departamento de Clínica Médica, Faculdade de Medicina de Botucatu
dc.format.extent1-4
dc.identifierhttp://dx.doi.org/10.14800/ics.648
dc.identifier.citationInflammation & Cell Signaling, v. 2, p. 1-4, 2015.
dc.identifier.doi10.14800/ics.648
dc.identifier.fileISSN2330-7803-2015-02-01-04.pdf
dc.identifier.issn2330-7803
dc.identifier.lattes8515265257310064
dc.identifier.lattes4868745446773753
dc.identifier.urihttp://hdl.handle.net/11449/136977
dc.language.isoeng
dc.relation.ispartofInflammation & Cell Signaling
dc.rights.accessRightsAcesso aberto
dc.sourceCurrículo Lattes
dc.subjectObesityen
dc.subjectKidneyen
dc.subjectOxidative stressen
dc.subjectAGEsen
dc.subjectRAGEen
dc.subjectInflammatory markersen
dc.titleThe role of oxidative stress in renal injury related to obesityen
dc.typeArtigo
dspace.entity.typePublication
unesp.author.lattes8515265257310064
unesp.author.lattes4868745446773753
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências, Botucatupt
unesp.departmentPatologia - FMBpt
unesp.departmentMicrobiologia e Imunologia - IBBpt
unesp.departmentClínica Médica - FMBpt

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Botucatu - FMB - Faculdade de Medicina
Botucatu - IBB - Instituto de Biociências