Contribuição ao protocolo de controle de qualidade da própolis e de seus extratos
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Data
2002-12-01
Autores
Bruschi, Marcos Luciano [UNESP]
Klein, Traudi
Lopes, Rafael Soares [UNESP]
Franco, Selma Lucy
Gremião, Maria Palmira Daflon [UNESP]
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Resumo
A quality control protocol for the analysis of propolis and its extracts is proposed in the present work. Propolis of Apis mellifera L. bees collected in beehives of an apiary located in the northwest of the Paraná State was triturated and submitted to the following analysis: particles medium size determination, loss of dry, ashes drift, waxes drift, drift of extractive (in water and in ethanol) and total flavonoids drift determination. Propolis ethanolic extracts (96 °GL) at 10% (w/w) and at 30% (w/w) were prepared and submitted to the determination of the pH, relative density, dry residue, alcoholic drift and total flavonoids drift determination. Propolis was analyzed, through High Performance Liquid Cromatography (HPLC). Comparing the obtained results with other works, it was observed that is possible to establish the intervals of values for parameters in order to evaluate the quality of a propolis sample and its extracts.
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Ethanolic extract, HPLC, Propolis, Quality control, alcohol, flavonoid, propolis, wax, ash, bee extract, chemical composition, clinical protocol, drug manufacture, extraction, high performance liquid chromatography, honeybee, nonhuman, particle size, quality control, water content
Como citar
Revista de Ciencias Farmaceuticas, v. 23, n. 2, p. 289-306, 2002.