Titanium dioxide and modified titanium dioxide by silver nanoparticles as an anti biofilm filler content for composite resins

dc.contributor.authorDias, Hércules Bezerra [UNESP]
dc.contributor.authorBernardi, Maria Inês Basso
dc.contributor.authorBauab, Taís Maria [UNESP]
dc.contributor.authorHernandes, Antônio Carlos
dc.contributor.authorde Souza Rastelli, Alessandra Nara [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2019-10-06T16:07:58Z
dc.date.available2019-10-06T16:07:58Z
dc.date.issued2019-02-01
dc.description.abstractObjective: The aim of this study was to evaluate the antibacterial activity of a composite resin modified by TiO2 and TiO2/Ag nanoparticles and their influence over different properties. Methods: TiO2 and TiO2/Ag NPs were synthesized by polymeric precursor and microwave-assisted hydrothermal methods and then, characterized by different techniques. Direct contact test was performed using Filtek™ Z350XT blended with 0.5; 1 and 2% (wt.) of NPs against Streptococcus mutans to determine the best concentration to the other tests. After that, the modified composite resin was tested against S. mutans 7-day biofilm (CFU/mL). Also, compressive and diametral tensile strength (n = 40), degree of conversion (n = 25) and surface roughness (n = 50) was performed. The data were analyzed by ANOVA and Tukey's test for multiple comparison at 5% significance level. Results: The direct contact test demonstrates that by increasing the nanoparticle content, the bacterial growth is significantly reduceed (p < 0.05). The inclusion of 2% of TiO2/Ag NPs significantly decreased (p < 0.05) the biofilm accumulation of S. mutans on the composite resin surface compared to the control Group. The TiO2 NPs treated with an organosilane increased compressive strength of composite resin (p < 0.05). Degree of conversion remained unchanged (p > 0.05) and the surface roughness increased with the NPs (p < 0.05), except for the TiO2 by polymeric precursor Group (p > 0.05). Significance: The development of an antibacterial dental restorative material that hinder S. mutans biofilm without sacrificing the mechanical and physical properties is desirable in dental material science.en
dc.description.affiliationDepartment of Restorative Dentistry Araraquara School of Dentistry University of São Paulo State — UNESP
dc.description.affiliationDepartment of Physics and Materials Science Physics Institute of São Carlos — IFSC University of São Paulo — USP
dc.description.affiliationDepartment of Biological Sciences Pharmaceutical Sciences School University of São Paulo State — UNESP
dc.description.affiliationUnespDepartment of Restorative Dentistry Araraquara School of Dentistry University of São Paulo State — UNESP
dc.description.affiliationUnespDepartment of Biological Sciences Pharmaceutical Sciences School University of São Paulo State — UNESP
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado do Amazonas
dc.format.extente36-e46
dc.identifierhttp://dx.doi.org/10.1016/j.dental.2018.11.002
dc.identifier.citationDental Materials, v. 35, n. 2, p. e36-e46, 2019.
dc.identifier.doi10.1016/j.dental.2018.11.002
dc.identifier.issn0109-5641
dc.identifier.scopus2-s2.0-85057584220
dc.identifier.urihttp://hdl.handle.net/11449/188435
dc.language.isoeng
dc.relation.ispartofDental Materials
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectBiofilms
dc.subjectComposite resin
dc.subjectNanoparticles
dc.subjectStreptococcus mutans
dc.subjectTitanium dioxide
dc.titleTitanium dioxide and modified titanium dioxide by silver nanoparticles as an anti biofilm filler content for composite resinsen
dc.typeArtigo
unesp.author.orcid0000-0002-1929-6003[3]

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