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Efeito do extrato aquoso de folhas de Polymnia sonchifolia (yacon) em ratas diabéticas

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dc.contributor.authorVolpato, G. T. [UNESP]
dc.contributor.authorVieira, F. L. [UNESP]
dc.contributor.authorDamasceno, D. C. [UNESP]
dc.contributor.authorCâmara, Francisco Luiz Araújo [UNESP]
dc.contributor.authorDi Stasi, L. C. [UNESP]
dc.contributor.authorLemonica, I. P. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUNIFAC
dc.date.accessioned2014-05-27T11:22:28Z
dc.date.available2014-05-27T11:22:28Z
dc.date.issued2007-05-01
dc.description.abstractPolymnia sonchifolia is a medicinal plant used as hypoglycemic agent and other ends. The aim was to evaluate the yacon effect on diabetes in Wistar female rats, which was divided in 4 groups: non-diabetic (n=24) given (gavage) 32.4 mg kg -1 of an aqueous extract of plant (treated group) or vehicle (non-treated group), and one diabetic group (n=24) with similar treatment compared to non-diabetic rats. Diabetes was induced using streptozotocin (i.v. route, 40 mg kg -1). Glycemia was monitored after rodent adaptation period, 15 days after diabetes induction, and each 10 days after yacon/vehicle in early treatment. During experiment period, body weights, food and water intake were daily measured. The rats (non-diabetic or diabetic) given yacon extract treatment presented no significant difference related with glycemia, body weight gain, and food and water intake. Thus, further studies such increase of rat number in agreement with different glycemic levels and increase of the plant extract dose are necessary.en
dc.description.affiliationLaboratório de Pesquisa Experimental de Ginecologia e Obstetrícia Depto. de Ginecologia e Obstetrícia Faculdade de Medicine de Botucatu - UNESP, Distrito de Rubião Jr. s/n., CEP: 18618-000 Botucatu - SP
dc.description.affiliationDisciplina de Educação Física Faculdades Integradas de Botucatu UNIFAC
dc.description.affiliationDepto. de Farmacologia Instituto de Biociências de Botucatu UNESP
dc.description.affiliationSetor de Horticultura Depto. de Produção Vegetal Faculdade de Ciências Agronômicas de Botucatu - UNESP
dc.description.affiliationUnespLaboratório de Pesquisa Experimental de Ginecologia e Obstetrícia Depto. de Ginecologia e Obstetrícia Faculdade de Medicine de Botucatu - UNESP, Distrito de Rubião Jr. s/n., CEP: 18618-000 Botucatu - SP
dc.description.affiliationUnespDepto. de Farmacologia Instituto de Biociências de Botucatu UNESP
dc.description.affiliationUnespSetor de Horticultura Depto. de Produção Vegetal Faculdade de Ciências Agronômicas de Botucatu - UNESP
dc.format.extent88-93
dc.identifierhttp://www.ibb.unesp.br/Home/Departamentos/Botanica/RBPM-RevistaBrasileiradePlantasMedicinais/artigo11_v9n2_88-93.pdf
dc.identifier.citationRevista Brasileira de Plantas Medicinais, v. 9, n. 2, p. 88-93, 2007.
dc.identifier.file2-s2.0-36348984998.pdf
dc.identifier.issn1516-0572
dc.identifier.lattes1697547325096457
dc.identifier.scopus2-s2.0-36348984998
dc.identifier.urihttp://hdl.handle.net/11449/69655
dc.language.isopor
dc.relation.ispartofRevista Brasileira de Plantas Medicinais
dc.relation.ispartofsjr0,199
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectDiabetes mellitus
dc.subjectPolymnia sonchifolia
dc.subjectRat
dc.subjectStreptozotocin
dc.subjectYacon
dc.subjectantidiabetic agent
dc.subjectherbaceous agent
dc.subjectPolymnia sonchifolia extract
dc.subjectstreptozocin
dc.subjectunclassified drug
dc.subjectanimal experiment
dc.subjectanimal model
dc.subjectbody weight
dc.subjectcontrolled study
dc.subjectdiabetes mellitus
dc.subjectdrug effect
dc.subjectfemale
dc.subjectfluid intake
dc.subjectfood intake
dc.subjectglucose blood level
dc.subjectmedicinal plant
dc.subjectnonhuman
dc.subjectrat
dc.subjectstreptozocin diabetes
dc.subjectweight gain
dc.subjectRattus
dc.subjectRodentia
dc.titleEfeito do extrato aquoso de folhas de Polymnia sonchifolia (yacon) em ratas diabéticaspt
dc.title.alternativeEffects of leaves of Polymnia sonchifolia (yacon) aqueous extract in diabetic ratsen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/rbpm/paboutj.htm#03
dspace.entity.typePublication
unesp.author.lattes1697547325096457
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Agronômicas, Botucatupt
unesp.departmentGinecologia e Obstetrícia - FMBpt
unesp.departmentHorticultura - FCApt
unesp.departmentFarmacologia - IBBpt

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Botucatu - FMB - Faculdade de Medicina
Botucatu - FCA - Faculdade de Ciências Agronômicas
Botucatu - IBB - Instituto de Biociências