Paracoccidioidomycosis: An Update from the Environment to Clinics

dc.contributor.authorde Oliveira, Haroldo Cesar
dc.contributor.authorde Paula e Silva, Ana Carolina Alves [UNESP]
dc.contributor.authorMarcos, Caroline Maria [UNESP]
dc.contributor.authorde Fátima da Silva, Julhiany [UNESP]
dc.contributor.authorScorzoni, Liliana [UNESP]
dc.contributor.authorAssato, Patricia Akemi [UNESP]
dc.contributor.authorRossi, Suélen Andreia
dc.contributor.institutionFundação Oswaldo Cruz (Fiocruz-PR)
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionGuarulhos University (UNG)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2023-07-29T13:42:11Z
dc.date.available2023-07-29T13:42:11Z
dc.date.issued2022-01-01
dc.description.abstractParacoccidioidomycosis is an endemic mycosis of great importance in Latin America caused by dimorphic fungi of the genus Paracoccidioides. Recent advances in the study of this mycosis reveal the Paracoccidioides genus as fungi that are difficult to treat and diagnose, with a great capacity to adapt and evade the environment of host cells, causing an invasive disease that is neglected in areas where it is endemic. This chapter aims to provide an overview of the fungi of this genus and the disease, bringing historical aspects and also the most recent advances in the study of this important mycosis, which has a great impact on public health in many countries in Latin America. This chapter will address issues such as the diversity of species of the Paracoccidioides genus, the thermal dimorphism, that allows the fungus to survive in the environment and the host, and its impact on the infectious process, virulence factors, and their relationship with the evasion capacity of the host immune system, as well as aspects associated with the disease such as clinical forms, pathogenesis, epidemiology, diagnosis and treatment.en
dc.description.affiliationInstituto Carlos Chagas Fundação Oswaldo Cruz (Fiocruz-PR), Parana
dc.description.affiliationDepartment of Dental Materials and Prosthodontics Sao Paulo State University (UNESP), Araraquara
dc.description.affiliationDepartment of Clinical Analysis School of Pharmaceutical Sciences São Paulo State University (UNESP), Araraquara
dc.description.affiliationDepartment of Infectious Diseases Dermatology Diagnostic Imaging and Radiotherapy Sao Paulo State University (UNESP), Botucatu
dc.description.affiliationDepartment of Biosciences and Oral Diagnosis Institute of Science and Technology Sao Paulo State University (UNESP), Sao Jose dos Campos
dc.description.affiliationNursing Post Graduation Guarulhos University (UNG), Guarulhos
dc.description.affiliationDepartment of Bioprocess and Biotechnology School of Agricultural Sciences São Paulo State University (UNESP), Botucatu
dc.description.affiliationDepartment of Microbiology Institute of Biomedical Sciences University of Sao Paulo (USP)
dc.description.affiliationUnespDepartment of Dental Materials and Prosthodontics Sao Paulo State University (UNESP), Araraquara
dc.description.affiliationUnespDepartment of Clinical Analysis School of Pharmaceutical Sciences São Paulo State University (UNESP), Araraquara
dc.description.affiliationUnespDepartment of Infectious Diseases Dermatology Diagnostic Imaging and Radiotherapy Sao Paulo State University (UNESP), Botucatu
dc.description.affiliationUnespDepartment of Biosciences and Oral Diagnosis Institute of Science and Technology Sao Paulo State University (UNESP), Sao Jose dos Campos
dc.description.affiliationUnespDepartment of Bioprocess and Biotechnology School of Agricultural Sciences São Paulo State University (UNESP), Botucatu
dc.format.extent165-200
dc.identifier.citationThe Book of Fungal Pathogens, p. 165-200.
dc.identifier.scopus2-s2.0-85148251436
dc.identifier.urihttp://hdl.handle.net/11449/248371
dc.language.isoeng
dc.relation.ispartofThe Book of Fungal Pathogens
dc.sourceScopus
dc.subjectDimorphic fungi
dc.subjectParacoccidioides spp
dc.subjectParacoccidioidomycosis
dc.subjectPCM clinical manifestations
dc.subjectPCM diagnosis
dc.subjectPCM treatment
dc.titleParacoccidioidomycosis: An Update from the Environment to Clinicsen
dc.typeCapítulo de livro
unesp.departmentAnálises Clínicas - FCFpt

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