Salivary alpha amylase and cortisol levels in children with global developmental delay and their relation with the expectation of dental care and behavior during the intervention

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dc.contributor.authorSantos, Márcio José Possari dos [UNESP]
dc.contributor.authorBernabé, Daniel Galera [UNESP]
dc.contributor.authorde Melo Stevanato Nakamune, Ana Claudia [UNESP]
dc.contributor.authorPerri, Silvia Helena Venturoli [UNESP]
dc.contributor.authorCoelho Avila de Aguiar, Sandra Maria Herondina [UNESP]
dc.contributor.authorOliveira, Sandra Helena Penha de [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2013-09-30T18:30:41Z
dc.date.accessioned2014-05-20T13:42:59Z
dc.date.available2013-09-30T18:30:41Z
dc.date.available2014-05-20T13:42:59Z
dc.date.issued2012-03-01
dc.description.abstractThe purpose of this study was to analyze the alpha-amylase (sAA) and cortisol levels in children with Global developmental delay (GDD) before and after dental treatment and its association with the children's behavior during treatment. The morning salivary cortisol levels and activity of sAA of 33 children with GDD were evaluated before and after dental treatment and were compared to 19 healthy children. The behavior of children with GDD during dental care was assessed by the Frankl scale. Children with GDD showed lower levels of sAA activity than healthy children, but this result was not significant. The salivary cortisol levels were similar between GOD and healthy children. GDD children showed increased levels of sAA (but not cortisol) prior to the dental treatment as compared to the post-treatment phase. GOD children who showed less favorable behavior during dental care had higher levels of sAA and salivary cortisol than GOD children with more favorable behavior, but only the sAA results were significant. In conclusion, GOD children show hyperactivity of the SNS-axis in anticipation of dental treatment which indicates the need for strategies to reduce their anxiety levels before and during dental care. (C) 2011 Elsevier Ltd. All rights reserved.en
dc.description.affiliationUNESP Univ Estadual Paulista, Sch Dent Aracatuba, Ctr Dent Care Persons Disabil CAOE, São Paulo, Brazil
dc.description.affiliationUNESP Univ Estadual Paulista, Dept Basic Sci, Pharmacol Lab, São Paulo, Brazil
dc.description.affiliationUNESP Univ Estadual Paulista, Oral Oncol Ctr, Sch Dent Aracatuba, São Paulo, Brazil
dc.description.affiliationUNESP Univ Estadual Paulista, Dept Basic Sci, Sch Dent Aracatuba, Discipline Biochem, São Paulo, Brazil
dc.description.affiliationUNESP Univ Estadual Paulista, Sch Vet Med Aracatuba, Dept Support Prod & Hlth Anim, Discipline Biostat, São Paulo, Brazil
dc.description.affiliationUNESP Univ Estadual Paulista, Sch Dent Aracatuba, Dept Pediat Dent & Social, Discipline Pediat, São Paulo, Brazil
dc.description.affiliationUNESP Univ Estadual Paulista, Sch Dent Aracatuba, Dept Basic Sci, Discipline Pharmacol, São Paulo, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Sch Dent Aracatuba, Ctr Dent Care Persons Disabil CAOE, São Paulo, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Dept Basic Sci, Pharmacol Lab, São Paulo, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Oral Oncol Ctr, Sch Dent Aracatuba, São Paulo, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Dept Basic Sci, Sch Dent Aracatuba, Discipline Biochem, São Paulo, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Sch Vet Med Aracatuba, Dept Support Prod & Hlth Anim, Discipline Biostat, São Paulo, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Sch Dent Aracatuba, Dept Pediat Dent & Social, Discipline Pediat, São Paulo, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Sch Dent Aracatuba, Dept Basic Sci, Discipline Pharmacol, São Paulo, Brazil
dc.format.extent499-505
dc.identifierhttp://dx.doi.org/10.1016/j.ridd.2011.10.015
dc.identifier.citationResearch In Developmental Disabilities. Oxford: Pergamon-Elsevier B.V. Ltd, v. 33, n. 2, p. 499-505, 2012.
dc.identifier.doi10.1016/j.ridd.2011.10.015
dc.identifier.issn0891-4222
dc.identifier.urihttp://hdl.handle.net/11449/14953
dc.identifier.wosWOS:000299403600025
dc.language.isoeng
dc.publisherPergamon-Elsevier B.V. Ltd
dc.relation.ispartofResearch in Developmental Disabilities
dc.relation.ispartofjcr1.820
dc.relation.ispartofsjr0,898
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectGlobal developmental delayen
dc.subjectDisabilitiesen
dc.subjectAnxietyen
dc.subjectAlpha-amylaseen
dc.subjectCortisolen
dc.subjectPaediatricen
dc.subjectDental treatmenten
dc.titleSalivary alpha amylase and cortisol levels in children with global developmental delay and their relation with the expectation of dental care and behavior during the interventionen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderPergamon-Elsevier B.V. Ltd
unesp.author.orcid0000-0003-0805-1120[6]
unesp.author.orcid0000-0002-1225-7749[2]
unesp.author.orcid0000-0001-5098-8406[3]
unesp.author.orcid0000-0001-5083-5557[4]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina Veterinária, Araçatubapt
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araçatubapt

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Coleções

Araçatuba - CAOE - Centro de Assistência Odontológica a Excepcionais
Araçatuba - COB - Centro de Oncologia Bucal
Artigos - Apoio, Produção e Saúde Animal - FMVA
Artigos - Ciências Básicas - FOA
Artigos - Odontologia Infantil e Social - FOA